Catalytic reduction of ortho- and para-azidonitrobenzenes via tert-butoxide ion mediated electron transfer

Article English OPEN
Carbone, Giorgio ; Burnley, James ; Moses, John E. (2013)

The reduction of a range of substituted azidonitrobenzene derivatives to the corresponding aniline is described. The chemoselective reaction proceeds cleanly and in good yield, generating minimal waste products. The process involves a thiazolium salt derived species which is proposed as a radical anion relay, with tert-butoxide as the stoichiometric reductant.
Share - Bookmark