An Integrated Analog Readout for Multi-Frequency Bioimpedance Measurements

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Kassanos, P. ; Constantinou, L. ; Triantis, I. F. ; Demosthenous, A. (2014)
  • Publisher: Institute of Electrical and Electronics Engineers
  • Related identifiers: doi: 10.1109/JSEN.2014.2315963
  • Subject: TK

Bioimpedance spectroscopy is used in a wide range of biomedical applications. This paper presents an integrated analog readout, which employs synchronous detection to perform galvanostatic multi-channel, multi-frequency bioimpedance measurements. The circuit was fabricated in a 0.35-μm CMOS technology and occupies an area of 1.52 mm2. The effect of random dc offsets is investigated, along with the use of chopping to minimize them. Impedance measurements of a known RC load and skin (using commercially available electrodes) demonstrate the operation of the system over a frequency range up to 1 MHz. The circuit operates from a ±2.5 V power supply and has a power consumption of 3.4-mW per channel.
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