Testing of a dual-mode microwave care regimen for hydrogel lenses

Article English OPEN
Crabbe, A ; Thompson, P (2004)
  • Publisher: Lippincott Williams & Wilkins

Purpose. To test the design of a patient care regimen for soft lenses that aims to provide the highest standards of disinfecting through use of domestic microwave cookers, while also providing storage equipment and solution that enable patients to follow a conventional cold disinfecting regimen when traveling. The cleaning efficacy of surfactant agents during microwave treatment was also considered. Methods. The microbiologic performance of the regimen and its disinfecting apparatus was tested according to the Food and Drug Administration (FDA) protocols for contact lens heat disinfectors. Subsequently, a prospective pilot clinical trial of the regimen involving 15 subjects was carried out to the protocols of the FDA and International Standards Organization 11,980:1997. Results. Lenses inoculated with 107 colony-forming units (cfu) of Enterococcus faecalis were disinfected to 0 cfu by a 12-s irradiation of a compact disinfecting case that held the lenses suspended in 12 ml saline. A proof of operation indicator performed correctly for all 10 cases tested. No adverse reactions were found in the pilot patient trial, using Renu multipurpose (Bausch & Lomb, Rochester, NY) as the test solution, and no statistically significant difference was found between test and control groups in respect of any sign. However, the greater incidence of edema, palpebral hyperemia, and lens front-surface deposition in the microwave test group may be clinically significant.
  • References (16)
    16 references, page 1 of 2

    1. Association of Contact Lens Manufacturers (UK) Market Trends 2002, unpublished internal bulletin.

    2. Crabbe A, Thompson P. Clinical trial of a patient-operated microwave care system for hydrogel contact lenses. Optom Vis Sci 2001; 78:605-9.

    3. Hiti K, Walochnik J, Faschinger C, Haller-Schober EM, Aspock H. Microwave treatment of contact lens cases contaminated with acanthamoeba. Cornea 2001;20:467-70.

    4. Harris MG, Rechberger J, Grant T, Holden BA. In-office microwave disinfection of soft contact lenses. Optom Vis Sci 1990;67:129-32.

    5. US Department of Health and Human Services, Food and Drug Administration, Center for Devices and Radiological Health. Premarket Notification (510k) Guidance Document for Contact Lens Care Products, 1997. Available at: http://www.fda.gov/cdrh/ode/ contlens.pdf. Accessed February 13, 2004:38-40, 43-5.

    6. Merindano MD, Marqués S, Lluch M, Gonzàles M, Saona C. Domestic microwave oven in contact lens disinfection. Contact Lens J 1990;18:241-6.

    7. Quesnel N, Simonet P, Giasson C. Stability of Crofilcon and Polymacon (clear and tinted) contact lenses after microwave irradiation. J Br Contact Lens Assoc 1996;19:49-54.

    8. Crabbe A, Thompson P. Effects of microwave irradiation on the parameters of hydrogel contact lenses. Optom Vis Sci 2001;78: 610-5.

    9. Claydon BE, Efron N. Non-compliance in contact lens wear. Ophthalmic Physiol Opt 1994;14:356-64.

    10. International Organization for Standardization. ISO 11980:1997: Ophthalmic Optics-Contact Lenses and Contact Lens Care Products-Guidance for Clinical Investigators. Geneva: International Organization for Standardization, 1997.

  • Metrics
    views in OpenAIRE
    views in local repository
    downloads in local repository

    The information is available from the following content providers:

    From Number Of Views Number Of Downloads
    Institutional Repository - IRUS-UK 0 49
Share - Bookmark