Copper(II)-Mediated Synthesis of Indolequinones from Bromoquinones and Enamines
Moody, Christopher J
- Publisher: WILEY-VCH Verlag
European Journal of Organic Chemistry,
(issn: 1434-193X, eissn: 1099-0690)
Cyclization | Full Papers | Nitrogen heterocycles | Copper | Quinones | Synthetic methods
The reaction of enamines and bromoquinones in the presence of copper(II) acetate and potassium carbonate results in a regiospecific synthesis of indolequinones. The reaction is broad in scope and scalable and provides a route to the core structure that is present in several biologically interesting natural and synthetic compounds.