Miniaturized optoelectronic tweezers controlled by GaN micro-pixel light emitting diode arrays

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Zarowna-Dabrowska, A. ; Neale, S.L. ; Massoubre, D. ; McKendry, J. ; Rae, B.R. ; Henderson, R.K. ; Rose, M.J. ; Yin, H. ; Cooper, J.M. ; Gu, E. ; Dawson, M.D. (2011)

A novel, miniaturized optoelectronic tweezers (OET) system has been developed using a CMOS-controlled GaN micro-pixelated light emitting diode (LED) array as an integrated micro-light source. The micro-LED array offers spatio-temporal and intensity control of the emission pattern, enabling the creation of reconfigurable virtual electrodes to achieve OET. In order to analyse the mechanism responsible for particle manipulation in this OET system, the average particle velocity, electrical field and forces applied to the particles were characterized and simulated. The capability of this miniaturized OET system for manipulating and trapping multiple particles including polystyrene beads and live cells has been successfully demonstrated.
  • References (14)
    14 references, page 1 of 2

    1. H. Xie, D. S. Haliyo, and S. Regnier, "A versatile atomic force microscope for three-dimensional nanomanipulation and nanoassembly," Nanotechnology 20, 215301 (2009).

    2. D. J. Stevenson, F. Gunn-Moore, and K. Dholakia, "Light forces the pace: optical manipulation for biophotonics," J. Biomed. Opt. 15, 041503 (2010).

    3. R. Pethig, "Review Article-Dielectrophoresis: Status of the theory, technology, and applications," Biomicrofluidics 4, 022811 (2010).

    4. G. Vieira, T. Henighan, A. Chen, A. J. Hauser, F. Y. Yang, J. J. Chalmers, and R. Sooryakumar, "Magnetic Wire Traps and Programmable Manipulation of Biological Cells," Phys. Rev. Lett. 103, 128101 (2009).

    5. Y. Yamakoshi, Y. Koitabashi, N. Nakajima, and T. Miwa, "Yeast cell trapping in ultrasonic wave field using ultrasonic contrast agent," Jpn. J. Appl. Phys. Part 1 - Regul. Pap. Brief Commun. Rev. Pap. 45, 4712-4717 (2006).

    6. P. Y. Chiou, A. T. Ohta, and M. C. Wu, "Massively parallel manipulation of single cells and microparticles using optical images," Nature 436, 370-372 (2005).

    7. S. L. Neale, M. Mazilu, J. I. B. Wilson, K. Dholakia, and T. F. Krauss, "The resolution of optical traps created by light induced dielectrophoresis (LIDEP)," Opt. Express 15, 12619-12626 (2007).

    8. H. Hwang, Y. J. Choi, W. Choi, S. H. Kim, J. Jang, and J. K. Park, "Interactive manipulation of blood cells using a lens-integrated liquid crystal display based optoelectronic tweezers system," Electrophoresis 29, 1203-1212 (2008).

    9. J. K. Valley, A. Jamshidi, A. T. Ohta, H. Y. Hsu, and M. C. Wu, "Operational regimes and physics present in optoelectronic tweezers," J. Microelectromech. Syst. 17, 342-350 (2008).

    10. J. J. D. McKendry, R. P. Green, A. E. Kelly, Z. Gong, B. Guilhabert, D. Massoubre, E. D. Gu, and M. D. Dawson, "High-Speed Visible Light Communications Using Individual Pixels in a Micro Light-Emitting Diode Array," IEEE Photonics Technol. Lett. 22, 1346-1348 (2010).

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