T cell protective immune responses against TB

Part of book or chapter of book English OPEN
Dockrell, HM (2014)
  • Publisher: Oxford University Press
  • Subject:
    mesheuropmc: biochemical phenomena, metabolism, and nutrition | chemical and pharmacologic phenomena

T cell immunity to MTB is both straightforward and incredibly complex. Th is chapter will focus on results obtained from studies of human T cells, but draw on studies in murine models where appropriate. It will provide a brief overview of the main roles played by T cells in immunity to MTB, highlight some areas of recent research, discuss some of the ways in which T cell immune responses can be measured in vaccine trials, and identify areas where further research is needed.
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