Remote Ischemic Preconditioning and Outcomes of Cardiac Surgery.

Article English OPEN
Hausenloy, DJ; Candilio, L; Evans, R; Ariti, C; Jenkins, DP; Kolvekar, S; Knight, R; Kunst, G; Laing, C; Nicholas, J; Pepper, J; Robertson, S; Xenou, M; Clayton, T; Yellon, DM; ERICCA Trial Investigators,; , COLLABORATORS; Goss, A; Desouza, A; Relvas, C; Morgan, H; Saunders, I; Donovan, J; Booth, J; Shah, M; Yates, M; Chawla, N; Stanger, O; Savory, R; Trimlett, R; ... view all 409 authors
(2015)

: Whether remote ischemic preconditioning (transient ischemia and reperfusion of the arm) can improve clinical outcomes in patients undergoing coronary-artery bypass graft (CABG) surgery is not known. We investigated this question in a randomized trial.<br/> : We conduc... View more
  • References (24)
    24 references, page 1 of 3

    1. Ferguson TB Jr, Hammill BG, Peter- the STS National Database Committee son ED, DeLong ER, Grover FL. A decade and the Duke Clinical Research Institute.

    of change - risk profiles and outcomes Ann Thorac Surg 2002;73:480-9.

    for isolated coronary artery bypass graft- 2. Thorsteinsson K, Fonager K, Mérie C, ing procedures, 1990-1999: a report from et al. Age-dependent trends in postopera3. Przyklenk K, Bauer B, Ovize M, Kloner RA, Whittaker P. Regional ischemic 'preconditioning' protects remote virgin myocardium from subsequent sustained coronary occlusion. Circulation 1993;87: 893-9.

    4. Hausenloy DJ, Yellon DM. Remote ischaemic preconditioning: underlying mechanisms and clinical application.

    Cardiovasc Res 2008;79:377-86.

    5. Sivaraman V, Pickard JM, Hausenloy DJ. Remote ischaemic conditioning: cardiac protection from afar. Anaesthesia 2015;70:732-48.

    6. Heusch G, Bøtker HE, Przyklenk K, Redington A, Yellon D. Remote ischemic conditioning. J Am Coll Cardiol 2015;65: 177-95.

    7. Kharbanda RK, Mortensen UM, White PA, et al. Transient limb ischemia induces remote ischemic preconditioning in vivo. Circulation 2002;106:2881-3.

    8. Hausenloy DJ, Mwamure PK, Venugopal V, et al. Effect of remote ischaemic preconditioning on myocardial injury in patients undergoing coronary artery bypass graft surgery: a randomised controlled trial. Lancet 2007;370:575-9.

    9. Venugopal V, Hausenloy DJ, Ludman A, et al. Remote ischaemic preconditioning reduces myocardial injury in patients undergoing cardiac surgery with coldblood cardioplegia: a randomised controlled trial. Heart 2009;95:1567-71.

  • Metrics
Share - Bookmark