publication . Other literature type . Article . 2015

Remote Ischemic Preconditioning and Outcomes of Cardiac Surgery

Hausenloy, DJ; Candilio, L; Evans, R; Ariti, C; Jenkins, DP; Kolvekar, S; Knight, R; Kunst, G; Laing, C; Nicholas, J; ...
  • Published: 08 Oct 2015
  • Publisher: Massachusetts Medical Society
  • Country: United Kingdom
Abstract
BACKGROUND: Whether remote ischemic preconditioning (transient ischemia and reperfusion of the arm) can improve clinical outcomes in patients undergoing coronary-artery bypass graft (CABG) surgery is not known. We investigated this question in a randomized trial. / METHODS: We conducted a multicenter, sham-controlled trial involving adults at increased surgical risk who were undergoing on-pump CABG (with or without valve surgery) with blood cardioplegia. After anesthesia induction and before surgical incision, patients were randomly assigned to remote ischemic preconditioning (four 5-minute inflations and deflations of a standard blood-pressure cuff on the upper...
Subjects
free text keywords: science & technology, life sciences & biomedicine, medicine, general & internal, general & internal medicine, bypass graft-surgery, percutaneous coronary intervention, controlled clinical-trial, artery-disease, metaanalysis, injury, cardioprotection, myocardium, isoflurane, improve, Cardiac surgery, medicine.medical_specialty, medicine, Percutaneous coronary intervention, medicine.medical_treatment, Stroke, medicine.disease, business.industry, business, Randomized controlled trial, law.invention, law, Myocardial infarction, Revascularization, Ischemic preconditioning, Anesthesia, Surgery, Ischemia
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publication . Other literature type . Article . 2015

Remote Ischemic Preconditioning and Outcomes of Cardiac Surgery

Hausenloy, DJ; Candilio, L; Evans, R; Ariti, C; Jenkins, DP; Kolvekar, S; Knight, R; Kunst, G; Laing, C; Nicholas, J; ...