publication . Article . Other literature type . 2017

Detection systems for antibody responses against herpes B virus.

Stefan Pöhlmann; Astrid Krüger; Wali Hafezi; Stefan Schneider; Jens Gruber; Michael Winkler; Artur Kaul;
Open Access English
  • Published: 01 Feb 2017 Journal: Primate Biology, volume 4, issue 1, pages 9-16 (issn: 2363-4707, eissn: 2363-4715, Copyright policy)
  • Publisher: Copernicus GmbH
Abstract
Herpes B virus (BV) infection is highly prevalent among adult Asian macaques and rarely causes severe disease in infected animals. In contrast, BV infection of humans can induce fatal encephalitis in the absence of treatment. Therefore, the development of diagnostic tests for specific and sensitive detection of antibodies against BV is an important task. The cross-reactivity of antibodies against BV with related simplex viruses of other primates may afford an opportunity to obtain sensitive detection systems without the need to work with the highly pathogenic BV. Moreover, it has been proposed that use of recombinant viral glycoproteins may allow for a detection...
Subjects
Medical Subject Headings: viruses
free text keywords: Research Article
Related Organizations
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