Prostate cancer in Alaska Native men, 1969-2003

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Snyder, Orrenzo B. ; Kelly, Janet J. ; Lanier, Anne P. (2012)
  • Publisher: Co-Action Publishing
  • Journal: International Journal of Circumpolar Health (issn: 1797-237X, eissn: 1239-9736)
  • Related identifiers: doi: 10.3402/ijch.v65i1.17891
  • Subject: prostate cancer, Alaska Native, American Indian/Alaska Native
    mesheuropmc: geographic locations

Objectives. The incidence of prostate cancer differs significantly between US race groups. In prior reviews of cancer in Alaska Natives, the incidence of prostate cancer has been observed to occur at a low rate compared to US Whites and Blacks. However, a detailed report of prostate cancer in this population has not been previously published. Study Design. Incidence of prostate cancer in Alaska Native men was determined for the time period 1969-2003 using data from the Alaska Native Tumor Registry. The registry is a population- based registry which participates in the National Cancer Institute Surveillance, Epidemiology and End Results Program, and has collected cancer information on Alaska Natives since 1969. Methods. Incidence rates were calculated for all Alaska Natives and for each of the three major ethnic groups (Aleut, Eskimo, Indian). Comparisons of incidence rates between Alaska Natives and US Whites were performed using odds ratios. Temporal changes were identified by a Chi square analysis for trend. Results. During the 35-year period of review, 332 Alaska Native men were diagnosed with prostate cancer. The age-adjusted incidence rate of 69.5 per 100 000 in Alaska Native men during 1994-2003 was significantly higher than the rate of 45.5 per 100 000 for the earlier period 1969- 1983. The US White rate for 1994-2002 of 169.5 per 100 000 was significantly higher than the rate for Alaska Native men for 1994-2003. Results of comparisons between Alaska Native ethnic groups for 1969-2003 showed that prostate cancer was highest in Indians and Aleuts and lowest among Eskimos. Conclusions. Compared to the US White population, the incidence of prostate cancer in Alaska Native men is significantly lower. Prostate cancer rates among Alaska Native ethnic groups differ. The reason for these differences remains undetermined.(Int J Circumpolar Health 2006;65(1):8-17.)Keywords: prostate cancer, Alaska Native, American Indian/Alaska Native
  • References (28)
    28 references, page 1 of 3

    1. Jemal A, Murray T, Samuels A, et al. Cancer statistics, 2003. CA Cancer J Clin 2003; 53:5-26.

    2. Farkas A, Schneider D, Perrotti M, et al. National trends in the epidemiology of prostate cancer, 1973 to 1994: Evidence for the effectiveness of prostatespecific antigen screening. Urol 1998; 52:444-448.

    3. Landis SH, Murray T, Bolden S, et al. Cancer statistics, 1998. CA Cancer J Clin 1998; 48:6-29.

    4. Lanier AP, Kelly JJ, Hock P, et al. Cancer in Alaska Natives, thirty-year report, 1969-1998. Alaska Med 2001; 43:87-115.

    5. Miller BA, Kolonel LN, Bernstein L, et al, editors. Racial/Ethnic Patterns of Cancer in the United States 1988-1992. Bethesda, MD, 1996; National Cancer Institute.

    6. Nutting PA, Freeman WL, Risser DR, et al. Cancer incidence among American Indians and Alaska Natives, 1980 through 1987. Am J Public Health 1993; 83:1589-1598.

    7. Gilliland FD, Key CR. Prostate cancer in American Indians, New Mexico, 1969 to 1994. J Urol 1998; 159:893-897.

    8. Prener A, Storm HH, Nielsen NH. Cancer of the male genital tract in circumpolar Inuit. Acta Oncol 1996; 35:589-593.

    9. Friborg J, Koch A, Wohlfarht J, Storm H, Melbye M. Cancer in Greenlandic Inuit 1973-1997: A cohort study. Int J Cancer 2003; 107:1017-1022.

    10. Marrett L, Chaudhry M. Cancer incidence and mortality in Ontario First Nations, 1968-1991 (Canada). Cancer Causes and Control 2003; 14: 259-268.

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