Intestinal Colonisation with Different Rabbit Enteropathogenic Escherichia coli Biotypes and Cross-Protection Induced by Different Strains
Devriese, L. A.
- Publisher: Microbial Ecology in Health and Disease
Microbial Ecology in Health and Disease
(issn: 1651-2235, eissn: 1651-2235)
mesheuropmc: biochemical phenomena, metabolism, and nutrition | digestive system | bacteria | bacterial infections and mycoses | parasitic diseases
Experimental infections with four different rabbit enteropathogenic Escherichia coli (EPEC) biotypes were carried out in EPEC free rabbits, and intestinal colonisation was assessed by measuring semi-quantitatively the rectal colonisation. When the animals were infected for the first time shortly after weaning, the excretion followed an approximately identical course with all four EPEC: at 3-9 d post-infection all rabbits excreted the infecting EPEC strain in high quantities, and continued to do so for 1-2 wks. Rabbits that had survived such a colonisation with one EPEC, were protected against colonisation with strains belonging to other EPEC groups.Keywords: E. coli; Rabbit EPEC; Intestinal colonisation; Cross-protection.