Appetite regulation - does it exist?

Article English OPEN
Erlanson-Albertsson, Charlotte (2000)
  • Publisher: Co-Action Publishing
  • Journal: Food & Nutrition Research (issn: 1654-661X, eissn: 1654-6628)
  • Related identifiers: doi: 10.3402/fnr.v44i0.1780

Appetite regulation and feeding behaviour are critical for survival. Through appetite regulation the proper amounts of fat, carbohydrate and protein are provided through specific signals, as has been demonstrated both in rodents and in man. Although feeding is necessary to provide energy, it also leads to severe perturbations in the homeostasis of the body. To help the body to maintain homeostasis various pre-meal events occur, such as the cephalic phase secretion of pancreatic juice, the production of satiety signals and the production of heat. The latter probably involves the action of uncoupling proteins present in the intestine. The diet-induced thermogenesis is hence important for achieving energy balance in the body. The increasing prevalence of obesity in the Western world is suggested to be a consequence of the overflow of tasty high-fat and sweet food items, which after ingestion override the original rules that we were once constructed for. Keywords: diet-induced thermogenesis, leptin, NPX opiates, uncouling protein
  • References (28)
    28 references, page 1 of 3

    Levine S BC: Why do we eat? A neural systems approach. Ann Rev Nutr 1997;17:597-619.

    Amsterdam: Elsevier Science, 1999:287-313.

    Mayer J: Bulletin of the New England Medical Center, Volume XIV, April-June 1952: The glucostatic theory of regulation of food intake and the problem of obesity (a review) [classical article]. Nutr Rev 1991;49:46-8.

    Kral JG: Surgical reduction of adipose tissue in the male Sprague-Dawley rat. Am J Physiol 1976;231:1090-6.

    Beck B, Jhanwar-Uniyal M, Burlet A, Chapleur-Chateau M, Leibowitz SF, Burlet C: Rapid and localized alterations of neuropeptide Y in discrete hypothalamic nuclei with feeding status. Brain Res 1990;528:245-9.

    Stanley BG, Daniel DR, Chin AS, Leibowitz SF: Paraventricular nucleus injections of peptide YY and neuropeptide Y preferentially enhance carbohydrate ingestion. Peptides 1985;6: 1205-11.

    7. Davies L, Marks JL: Role of hypothalamic neuropeptide Y gene expression in body weight regulation. Am J Physiol 1994;266:R1687-91.

    8. Wilding JP, Ajala MO, Lambert PD, Bloom SR: Additive effects of lactation and food restriction to increase hypothalamic neuropeptide Y mRNA in rats. J Endocrinol 1997;152:365-9.

    9. Morley JE, Levine AS, Yim GK, Lowy MT: Opioid modulation of appetite. Neurosci Biobehav Rev 1983;7:281-305.

    10. Barton C, Lin L, York DA, Bray GA: Differential effects of enterostatin, galanin and opioids on high-fat diet consumption. Brain Res 1995;702:55-60.

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