publication . Article . 2007

Impact of Intracoronary Cell Therapy on Left Ventricular Function in the Setting of Acute Myocardial Infarction. A Collaborative Systematic Review and Meta-Analysis of Controlled Clinical Trials

Michael J. Lipinski; Giuseppe G.L. Biondi-Zoccai; Antonio Abbate; Reena Khianey; Imad Sheiban; Jozef Bartunek; Marc Vanderheyden; Hyo-Soo Kim; Hyun-Jae Kang; Bodo E. Strauer; ...
Open Access English
  • Published: 01 Oct 2007 Journal: Journal of the American College of Cardiology, issue 18, pages 1,761-1,767 (issn: 07351097, Copyright policy)
  • Publisher: American College of Cardiology Foundation. Published by Elsevier Inc.
Abstract
ObjectivesWe aimed to perform a meta-analysis of clinical trials on intracoronary cell therapy after acute myocardial infarction (AMI).BackgroundIntracoronary cell therapy continues to be evaluated in the setting of AMI with variable impact on left ventricular ejection fraction (LVEF).MethodsWe searched the CENTRAL, mRCT, and PubMed databases for controlled trials reporting on intracoronary cell therapy performed in patients with a recent AMI (≤14 days), revascularized percutaneously, with follow-up of ≥3 months. The primary end point was change in LVEF, and secondary end points were changes in infarct size, cardiac dimensions, and dichotomous clinical outcomes....
Subjects
Medical Subject Headings: cardiovascular diseases
free text keywords: Cardiology and Cardiovascular Medicine, Clinical trial, Randomized controlled trial, law.invention, law, Meta-analysis, Myocardial infarction, medicine.disease, medicine, Ejection fraction, business.industry, business, Internal medicine, medicine.medical_specialty, Heart disease, Percutaneous coronary intervention, medicine.medical_treatment, Clinical endpoint, Cardiology
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