D-MANNITOL FROM THE FRAXINUS EXCELSIOR

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Керимли (Kerimli), Эльвин (El'vin) Гаджи оглу (Gadzhi oglu) ; Серкеров (Serkerov), Сираджеддин (Siradzheddin) Велиевич (Velievich) (2016)
  • Publisher: Altai State University
  • Journal: Khimiia rastitel'nogo syr'ia (Chemistry of plant raw material) (issn: 1029-5143, eissn: 1029-5151)
  • Related identifiers: doi: 10.14258/jcprm.2016011031
  • Subject: Fraxinus excelsior; European ash; barks; fruits; leaves; extraction; acetylation; mannitol | Fraxinus excelsior, ясень обыкновенный, кора, плоды, листья, экстракция, ацетилирование, маннитол

The result of chemical study of the barks, fruits and leaves of Fraxinus excelsior L. are discussed in this article. The individual substance has been separated as crystallic form from the sum of alcholic extraction by column chromatography (neutral Al2O3). The chemical structure of this substance is С6H14O6 m.p. 175,0-176,0 °С, [α]D20+20 (c10, H2O).On the basis of chemical and spectral (IR, NMR, 1H, 13C, 13C Dept 135 and mass spectra) data of the separated substance and its hexaacetyl derivative obtained by interpretation found that it corresponds to the structure of (2R, 3R, 4R, 5R)-hexane-1,2,3,4,5,6-hexol (D-mannitol).Analysis of substance by this method 13C and 13C Dept 135 showed that due to the effect of symmetry and characteristic of hexitol in spectra are shown only three characterizing six carbon atoms instead of the expected six signals.The substance in the raw material: in the cortex – 0,62%, fruits – 0,40%, leaves – 0,42%
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