THE ANTIOXIDANT AND ELECTROCHEMICAL PROPERTIES OF THE NOVEL WATER SOLUBLE BIOFLAVONOID DERIVATIVE – DIHYDROQUERCETIN MONOSUCCINATE

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Баженов, Борис Николаевич ; Елисеева, Галина Дмитриевна ; Золотарёв, Егор Евгеньевич ; Кашевский, Алексей Валерьевич ; Сафронов, Александр Юрьевич ; Финкельштейн, Борис Львович (2013)
  • Publisher: Altai State University
  • Journal: Khimiia rastitel'nogo syr'ia (Chemistry of plant raw material) (issn: 1029-5143, eissn: 1029-5151)
  • Related identifiers: doi: 10.14258/jcprm.1303107
  • Subject: dihydroquercetin monosuccinate, antioxidant activity, cyclic voltammetry | моносукцинат дигидрокверцетина, антиоксидантная активность, циклическая вольтамперометрия

The native antioxidant dihydroquercetin has a wide spectrum of pharmacological properties, however its low solubility make cense for getting the water soluble derivatives maintaining a high antioxidant activity. A possible strategy to get this result could be a hydrophilic moiety (such as succinic acid residue) insertion into the flavonoid molecule. Being more soluble in water the novel synthetic derivative of the bioflavonoid – dihydriquercetin monosuccinate maintains a high antioxidant activity confirmed by means of TEAC method and the voltammetry data. Dihydriquercetin monosuccinate redox transformations on a graphite electrode proving the high antioxidant activity of the studied compound, at the same time demonstrate a complex character. Better understanding of this character is a possible way to the dihydriquercetin monosuccinate redox parameters control under different conditions and/or in the different environments.
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