project . 2019 - 2021 . On going

Validation and feasibility of a novel, simple and rapid assay to detect cholera in resource poor settings and outbreak situations

Wellcome Trust
  • Funder: Wellcome TrustProject code: 215673
  • Funded under: Innovations Funder Contribution: 349,999 GBP
  • Status: On going
  • Start Date
    16 Sep 2019
    End Date
    15 Sep 2021
Description
<p>Prompt identification of cholera cases facilitates rapid outbreak responses in the short<br> term, while providing reliable surveillance data to guide long-term policies and<br> interventions. To this end, microbiological stool culture, the current recognized gold<br> standard for the diagnosis of cholera has significant limitations. Rapid diagnostic tests<br> (ROTs) represent promising alternatives for the diagnosis of cholera in areas with limited<br> laboratory infrastructure. Despite their advantages, there are also significant limitations&nbsp;to current ROTs for cholera. Most studies conducted with the current ROTs,<br> demonstrate suboptimal performanc...
Description
<p>Prompt identification of cholera cases facilitates rapid outbreak responses in the short<br> term, while providing reliable surveillance data to guide long-term policies and<br> interventions. To this end, microbiological stool culture, the current recognized gold<br> standard for the diagnosis of cholera has significant limitations. Rapid diagnostic tests<br> (ROTs) represent promising alternatives for the diagnosis of cholera in areas with limited<br> laboratory infrastructure. Despite their advantages, there are also significant limitations&nbsp;to current ROTs for cholera. Most studies conducted with the current ROTs,<br> demonstrate suboptimal performanc...
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