project . 2018 - 2023 . On going

StemCellHabitat

Metabolic and Timed Control of Stem Cell Fate in the Developing Animal
Open Access mandate for Publications European Commission
  • Funder: European CommissionProject code: 759853 Call for proposal: ERC-2017-STG
  • Funded under: H2020 | ERC | ERC-STG Overall Budget: 1,697,490 EURFunder Contribution: 1,697,490 EUR
  • Status: On going
  • Start Date
    01 Feb 2018
    End Date
    31 Jan 2023
  • Detailed project information (CORDIS)
  • Open Access mandate
    Research Data: No
Description
Stem cell (SC) proliferation during development requires tight spatial and temporal regulation to ensure correct cell number and right cell types are formed at the proper positions. Currently very little is known about how SCs are regulated during development. Specifically, it is unclear how SC waves of proliferation are regulated and how the fate of their progeny changes during development. In addition, it has recently become evident that metabolism provides additional complexity in cell fate regulation, highlighting the need for integrating metabolic information across physiological levels. This project will answer the question of how the combination of metabo...
Description
Stem cell (SC) proliferation during development requires tight spatial and temporal regulation to ensure correct cell number and right cell types are formed at the proper positions. Currently very little is known about how SCs are regulated during development. Specifically, it is unclear how SC waves of proliferation are regulated and how the fate of their progeny changes during development. In addition, it has recently become evident that metabolism provides additional complexity in cell fate regulation, highlighting the need for integrating metabolic information across physiological levels. This project will answer the question of how the combination of metabo...
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