project . 2019 - 2024 . On going

Tumor microbiome

The tumor microbial communities: Characterization, effects and translational opportunities
Open Access mandate for Publications European Commission
  • Funder: European CommissionProject code: 818086 Call for proposal: ERC-2018-COG
  • Funded under: H2020 | ERC | ERC-COG Overall Budget: 2,000,000 EURFunder Contribution: 2,000,000 EUR
  • Status: On going
  • Start Date
    01 May 2019
    End Date
    30 Apr 2024
  • Detailed project information (CORDIS)
  • Open Access mandate
    Research Data: No
Description
The human body is host to a huge number of bacteria. While bacteria were first detected in human tumors over 150 years ago, our knowledge about their number, identity or effects in different human tumor types is still mostly rudimentary. Over the last few years we focused on studying the tumor microbiome. We developed multiple methods to characterize and visualize intra-tumor bacteria, taking special measures to tell apart true tumor-bacteria from contamination. Profiling over 1,800 human tumors and normal adjacent tissues demostrated that bacteria are prevalent in many tumor types and that each tumor type has a unique microbial signature. This application aims ...
Description
The human body is host to a huge number of bacteria. While bacteria were first detected in human tumors over 150 years ago, our knowledge about their number, identity or effects in different human tumor types is still mostly rudimentary. Over the last few years we focused on studying the tumor microbiome. We developed multiple methods to characterize and visualize intra-tumor bacteria, taking special measures to tell apart true tumor-bacteria from contamination. Profiling over 1,800 human tumors and normal adjacent tissues demostrated that bacteria are prevalent in many tumor types and that each tumor type has a unique microbial signature. This application aims ...
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