project . 2020 - 2020 . Closed

LCxLCProt

Comprehensive two-dimensional liquid chromatography for the characterization of protein biopharmaceuticals at the protein level
Open Access mandate for Publications European Commission
  • Funder: European CommissionProject code: 843702 Call for proposal: H2020-MSCA-IF-2018
  • Funded under: H2020 | MSCA-IF-EF-ST Overall Budget: 89,160 EURFunder Contribution: 89,160 EUR
  • Status: Closed
  • Start Date
    01 Jan 2020
    End Date
    31 Dec 2020
  • Detailed project information (CORDIS)
  • Open Access mandate
    Research Data: No
Description
Protein biopharmaceuticals, which globally represent about 20 % of the total pharmaceutical market, are becoming increasingly popular in the treatment of various diseases. Experts forecast that over 50 % of new drug approvals in the next decade will be for biologics, especially monoclonal antibodies. Very accurate structural characterization and purity analysis is required during both the development of the new drugs, and later during manufacturing for quality control purposes. Biopharmaceutical protein molecules are very large and heterogeneous, which makes their characterization very difficult. The goal of this project is to develop novel methods for the chara...
Description
Protein biopharmaceuticals, which globally represent about 20 % of the total pharmaceutical market, are becoming increasingly popular in the treatment of various diseases. Experts forecast that over 50 % of new drug approvals in the next decade will be for biologics, especially monoclonal antibodies. Very accurate structural characterization and purity analysis is required during both the development of the new drugs, and later during manufacturing for quality control purposes. Biopharmaceutical protein molecules are very large and heterogeneous, which makes their characterization very difficult. The goal of this project is to develop novel methods for the chara...
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