project . 2019 - 2023 . On going

iPC

individualizedPaediatricCure: Cloud-based virtual-patient models for precision paediatric oncology
Open Access mandate for Publications and Research DataOpen Access mandate for ... European Commission
  • Funder: European CommissionProject code: 826121 Call for proposal: H2020-SC1-DTH-2018-1
  • Funded under: H2020 | RIA Overall Budget: 15,066,500 EURFunder Contribution: 14,748,400 EUR
  • Status: On going
  • Start Date
    01 Jan 2019
    End Date
    31 May 2023
  • Detailed project information (CORDIS)
Description
Effective personalized medicine for paediatric cancers must address a multitude of challenges, including domain-specific challenges. To overcome these challenges, we propose a comprehensive computational effort to combine knowledge-base, machine-learning, and mechanistic models to predict optimal standard and experimental therapies for each child. Our approach is based on virtual patient models–in-silico avatars whose analysis can inform personalized diagnostics and recommend treatments. Our platform will also allow care givers to query models and infer benefits and drawbacks for specific treatment combinations for each child. To construct these models, we will ...
Description
Effective personalized medicine for paediatric cancers must address a multitude of challenges, including domain-specific challenges. To overcome these challenges, we propose a comprehensive computational effort to combine knowledge-base, machine-learning, and mechanistic models to predict optimal standard and experimental therapies for each child. Our approach is based on virtual patient models–in-silico avatars whose analysis can inform personalized diagnostics and recommend treatments. Our platform will also allow care givers to query models and infer benefits and drawbacks for specific treatment combinations for each child. To construct these models, we will ...
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