project . 2016 - 2021 . Closed

GeneREFORM

Genetically Encoded Multicolor Reporter Systems For Multiplexed MRI
Open Access mandate for Publications European Commission
  • Funder: European CommissionProject code: 677715 Call for proposal: ERC-2015-STG
  • Funded under: H2020 | ERC | ERC-STG Overall Budget: 1,478,280 EURFunder Contribution: 1,478,280 EUR
  • Status: Closed
  • Start Date
    01 May 2016
    End Date
    30 Apr 2021
  • Detailed project information (CORDIS)
  • Open Access mandate
    Research Data: No
Description
In order to fully understand the complexity of biological processes that are reflected by simultaneous occurrences of intra and inter-cellular events, multiplexed imaging platforms are needed. Fluorescent reporter genes, with their “multicolor” imaging capabilities, have revolutionized science and their founders have been awarded the Nobel Prize. Nevertheless, the light signal source of these reporters, which restricts their use in deep tissues and in large animals (and potentially in humans), calls for alternatives. Reporter genes for MRI, although in their infancy, showed several exceptionalities, including the ability to longitudinal study the same subject wi...
Description
In order to fully understand the complexity of biological processes that are reflected by simultaneous occurrences of intra and inter-cellular events, multiplexed imaging platforms are needed. Fluorescent reporter genes, with their “multicolor” imaging capabilities, have revolutionized science and their founders have been awarded the Nobel Prize. Nevertheless, the light signal source of these reporters, which restricts their use in deep tissues and in large animals (and potentially in humans), calls for alternatives. Reporter genes for MRI, although in their infancy, showed several exceptionalities, including the ability to longitudinal study the same subject wi...
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