project . 2022 - 2026 . Not started

InSpIRe

Intact SynaPtic Imaging in REal-time
Open Access mandate for Publications European Commission
  • Funder: European CommissionProject code: 101002490 Call for proposal: ERC-2020-COG
  • Funded under: H2020 | ERC | ERC-COG Overall Budget: 2,380,000 EURFunder Contribution: 2,380,000 EUR
  • Status: Not started
  • Start Date
    01 Jan 2022
    End Date
    31 Dec 2026
  • Detailed project information (CORDIS)
  • Open Access mandate
    Research Data: No
Description
Modern fluorescence microscopy can provide rapid, real-time functional imaging of brain activities (light sheet) or to visualize with high definition and specificity the synaptic organization (super resolution, expansion). However, rapidity and precision are still too far apart to allow studies of fast dynamics with intra-synaptic precision mainly due to incompatible optical and probes requirements in current technologies. My aim is to fill this gap with the development of an optical platform, named InSpIRe, which allows real-time volumetric imaging of brain tissues with intra-synaptic level of details thanks to a new optical scheme coupled to the photo-switchin...
Partners
Description
Modern fluorescence microscopy can provide rapid, real-time functional imaging of brain activities (light sheet) or to visualize with high definition and specificity the synaptic organization (super resolution, expansion). However, rapidity and precision are still too far apart to allow studies of fast dynamics with intra-synaptic precision mainly due to incompatible optical and probes requirements in current technologies. My aim is to fill this gap with the development of an optical platform, named InSpIRe, which allows real-time volumetric imaging of brain tissues with intra-synaptic level of details thanks to a new optical scheme coupled to the photo-switchin...
Partners
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