project . 2016 - 2021 . Closed

inHForm

Integrative omics of heart failure to inform discovery of novel drug targets and clinical biomarkers
Open Access mandate for Publications European Commission
  • Funder: European CommissionProject code: 679242 Call for proposal: ERC-2015-STG
  • Funded under: H2020 | ERC | ERC-STG Overall Budget: 1,496,620 EURFunder Contribution: 1,496,620 EUR
  • Status: Closed
  • Start Date
    01 Apr 2016
    End Date
    31 Mar 2021
  • Detailed project information (CORDIS)
  • Open Access mandate
    Research Data: No
Description
Heart failure is a leading cause of morbidity and mortality in the aging European populations. It is the end-stage of myocardial and valvular disease, arising from loss of viable or functional muscle cells in the heart. Therapy is complicated by the multitude of causes and comorbidities of heart failure. New therapeutic targets and clinical biomarkers to individually tailor therapy (‘precision medicine’) are greatly needed. This research program aims to realize the promise of precision medicine by applying an integrated proteomic, genomic and epidemiological approach to the underlying causes, mechanisms and consequences for heart failure. The program builds on u...
Description
Heart failure is a leading cause of morbidity and mortality in the aging European populations. It is the end-stage of myocardial and valvular disease, arising from loss of viable or functional muscle cells in the heart. Therapy is complicated by the multitude of causes and comorbidities of heart failure. New therapeutic targets and clinical biomarkers to individually tailor therapy (‘precision medicine’) are greatly needed. This research program aims to realize the promise of precision medicine by applying an integrated proteomic, genomic and epidemiological approach to the underlying causes, mechanisms and consequences for heart failure. The program builds on u...
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