project . 2021 - 2023 . Not started

MsInfection

Mechanistic basis of host infection and intracellular development in microsporidia
Open Access mandate for Publications and Research DataOpen Access mandate for ... European Commission
  • Funder: European CommissionProject code: 101033469 Call for proposal: H2020-MSCA-IF-2020
  • Funded under: H2020 | MSCA-IF-EF-ST Overall Budget: 191,852 EURFunder Contribution: 191,852 EUR
  • Status: Not started
  • Start Date
    01 Nov 2021
    End Date
    31 Oct 2023
  • Detailed project information (CORDIS)
Description
Microsporidia are emerging pathogens of high priority that infect humans, and most animals. Microsporidiosis can be life-threatening and cause severe damage in the eyes, brain, muscles, respiratory, and urinary tracts. These obligate intracellular parasites also present a unique case of reductive and divergent evolution. They possess the smallest eukaryotic genome and unique cellular features such as the smallest eukaryotic cytoplasmic ribosomes and a specialised infection apparatus, the polar tube. Inside the host, microsporidia replicate through distinct life stages to form infective spores that are released into the environment upon host cell lysis. However, ...
Description
Microsporidia are emerging pathogens of high priority that infect humans, and most animals. Microsporidiosis can be life-threatening and cause severe damage in the eyes, brain, muscles, respiratory, and urinary tracts. These obligate intracellular parasites also present a unique case of reductive and divergent evolution. They possess the smallest eukaryotic genome and unique cellular features such as the smallest eukaryotic cytoplasmic ribosomes and a specialised infection apparatus, the polar tube. Inside the host, microsporidia replicate through distinct life stages to form infective spores that are released into the environment upon host cell lysis. However, ...
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