project . 2015 - 2018 . Closed

BURK-6

Investigation of the Type VI secretion system-associated toxins of Burkholderia thailandensis
Open Access mandate for Publications European Commission
  • Funder: European CommissionProject code: 657766 Call for proposal: H2020-MSCA-IF-2014
  • Funded under: H2020 | MSCA-IF-GF Overall Budget: 276,107 EURFunder Contribution: 276,107 EUR
  • Status: Closed
  • Start Date
    01 Sep 2015
    End Date
    31 Aug 2018
  • Detailed project information (CORDIS)
  • Open Access mandate
    Research Data: No
Description
Secretion systems are evolved machineries enabling bacteria to deliver toxins and virulence factors, called effectors, into target cells to enable the onset of infectious diseases. Uncovering these effectors is essential for the understanding of bacterial pathogenesis and the establishment of appropriate therapeutic strategies to tackle infectious diseases. The recently identified Type Six Secretion System (T6SS) is conserved in environmental and pathogenic Gram-negative bacteria. The T6SS is an organelle structurally akin to an intracellular and membrane-bound contractile phage tail used for the delivery of toxins into prokaryotic and eukaryotic target cells. T...
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Description
Secretion systems are evolved machineries enabling bacteria to deliver toxins and virulence factors, called effectors, into target cells to enable the onset of infectious diseases. Uncovering these effectors is essential for the understanding of bacterial pathogenesis and the establishment of appropriate therapeutic strategies to tackle infectious diseases. The recently identified Type Six Secretion System (T6SS) is conserved in environmental and pathogenic Gram-negative bacteria. The T6SS is an organelle structurally akin to an intracellular and membrane-bound contractile phage tail used for the delivery of toxins into prokaryotic and eukaryotic target cells. T...
Partners
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