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Other research product . Other ORP type . 2020

Methodological approaches for personalised medicine: protocol for a series of scoping reviews

Banzi, Rita; Gerardi, Chiara; Fratelli, Maddalena; Garcia, Paula; Torres, Teresa; Abad, Josep Maria Haro; Niubo, Albert Sanchez; +8 Authors
Open Access
Published: 30 Apr 2020
Publisher: Zenodo
Abstract

This is the protocol for a series of scoping reviews that will map the general concept of methods for personalised medicine, to set the basis for the discussion on robustness and reproducibility of personalised medicine development programmes. The final goal is the identification of standards and needs in terms of methodology of data generation, management, analysis and interpretation to improve clinical studies in personalised medicine. For the purpose of this review, four main aspects of the general concept of personalised medicine will be analysed: Methods for stratification and validation cohorts Methods for machine learning applied to stratification Pre-clinical methods for translational development of treatment options and treatments selection Methods for clinical trials in personalised medicine

Subjects

personalised medicine, methods, clinical trials, scoping review

Funded by
EC| PERMIT
Project
PERMIT
PERsonalised MedicIne Trials
  • Funder: European Commission (EC)
  • Project Code: 874825
  • Funding stream: H2020 | CSA
Validated by funder
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