Phase 1 Trial of Malaria Transmission Blocking Vaccine Candidates Pfs25 and Pvs25 Formulated with Montanide ISA 51

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Wu, Yimin; D. Ellis, Ruth; Shaffer, Donna; Fontes, Erica; M. Malkin, Elissa; Mahanty, Siddhartha; P. Fay, Michael; Narum, David; Rausch, Kelly; P. Miles, Aaron; Aebig, Joan; Orcutt, Andrew; Muratova, Olga; Song, Guanhong; Lambert, Lynn; Zhu, Daming; Miura, Kazutoyo; Long, Carole; Saul, Allan; H. Miller, Louis; P. Durbin, Anna;
  • Publisher: Figshare
  • Related identifiers: doi: 10.1371/journal.pone.0002636
  • Subject: candidates | pvs25 | blocking | isa | Cancer | pfs25 | montanide | malaria | 51 | Immunology | formulated
    mesheuropmc: parasitic diseases

<div><h3>Background</h3><p>Pfs25 and Pvs25, surface proteins of mosquito stage of the malaria parasites <em>P. falciparum</em> and <em>P. vivax,</em> respectively, are leading candidates for vaccines preventing malaria transmission by mosquitoes. This single blinded, do... View more
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