Tracheal Dysplasia Precedes Bronchial Dysplasia in Mouse Model of N-Nitroso Trischloroethylurea Induced Squamous Cell Lung Cancer

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Ghosh, Moumita; D. Dwyer-Nield, Lori; B. Kwon, Jennifer; Barthel, Lea; J. Janssen, William; T. Merrick, Daniel; L. Keith, Robert;
(2015)
  • Publisher: Figshare
  • Related identifiers: doi: 10.1371/journal.pone.0122823
  • Subject: Club cell secretory protein | NTCU | tunel | basal cell metaplasia | dysplasia | Tracheal Dysplasia Precedes Bronchial Dysplasia | scc | Uncategorised | lung cancer death | ccsp | 32 weeks | epithelium | epithelial cell phenotypes | basal cells | future chemoprevention studies
    mesheuropmc: respiratory system

<div><p>Squamous cell lung cancer (SCC) is the second leading cause of lung cancer death in the US and has a 5-year survival rate of only 16%. Histological changes in the bronchial epithelium termed dysplasia are precursors to invasive SCC. However, the cellular mechani... View more
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