Neuromelanins of Human Brain Have Soluble and Insoluble Components with Dolichols Attached to the Melanic Structure

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Engelen, Mireille ; Vanna, Renzo ; Bellei, Chiara ; A. Zucca, Fabio ; Wakamatsu, Kazumasa ; Monzani, Enrico ; Ito, Shosuke ; Casella, Luigi ; Zecca, Luigi
  • Publisher: Figshare
  • Related identifiers: doi: 10.1371/journal.pone.0048490
  • Subject: Chemistry | insoluble | components | Neuroscience | dolichols | Biochemistry | attached | soluble | melanic | neuromelanins | structure
    mesheuropmc: nervous system

<div><p>Neuromelanins (NMs) are neuronal pigments of melanic-lipidic type which accumulate during aging. They are involved in protective and degenerative mechanisms depending on the cellular context, however their structures are still poorly understood. NMs from nine hu... View more
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