Immunoglobulin Heavy Chain Exclusion in the Shark

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Malecek, Karolina; Lee, Victor; Feng, Wendy; Li Huang, Jing; F Flajnik, Martin; Ohta, Yuko; Hsu, Ellen;
  • Publisher: Figshare
  • Related identifiers: doi: 10.1371/journal.pbio.0060157
  • Subject: Genetics | immunoglobulin | exclusion | Immunology
    mesheuropmc: chemical and pharmacologic phenomena

<div><p>The adaptive immune system depends on specific antigen receptors, immunoglobulins (Ig) in B lymphocytes and T cell receptors (TCR) in T lymphocytes. Adaptive responses to immune challenge are based on the expression of a single species of antigen receptor per ce... View more
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