Monitoring of Pentoxifylline Thermal Behavior by Novel Simultaneous Laboratory Small and Wide X-Ray Scattering (SWAXS) and Differential Scanning Calorimetry (DSC)

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Hodzic, Aden; Kriechbaum, Manfred; Schrank, Simone; Reiter, Franz;
(2016)
  • Publisher: Figshare
  • Related identifiers: doi: 10.1371/journal.pone.0159840
  • Subject: Biophysics | Biochemistry | Biotechnology | Inorganic Chemistry | Science Policy | enthalpy values | scanning rate | Wide X-Ray Scattering | laboratory instrument | phase transitions | S 3-MicroCaliX | laboratory tool | Differential Scanning Calorimetry | API purity quality control | SWAXS | scanning rates | ingredient | non-complex samples | purity quality control | X-ray spectra | DSC | time-resolved X-ray | API purity
    • FOR: 39999 Chemical Sciences not elsewhere classified | 29999 Physical Sciences not elsewhere classified

<div><p>The thermal and structural evolutions associated to active pharmaceutical ingredient (API) purity are monitored using a laboratory instrument (S3-MicroCaliX) allowing simultaneous time-resolved X-ray scattering at both wide and small angles (SWAXS) as a function... View more
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