The Confounding Effect of Population Structure on Bayesian Skyline Plot Inferences of Demographic History

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Heller, Rasmus; Chikhi, Lounes; Redlef Siegismund, Hans;
  • Publisher: Figshare
  • Related identifiers: doi: 10.1371/journal.pone.0062992
  • Subject: Biotechnology | Ecology | Science Policy | software package BEAST | population structure | skyline plot inferences | African buffalo population | Bayesian skyline plots | sampling strategy | population size change | BSP | Bayesian Skyline Plot Inferences | DNA sequence data
    • FOR: 59999 Environmental Sciences not elsewhere classified | 69999 Biological Sciences not elsewhere classified | 19999 Mathematical Sciences not elsewhere classified

<div><p> </p><p>Many coalescent-based methods aiming to infer the demographic history of populations assume a single, isolated and panmictic population (i.e. a Wright-Fisher model). While this assumption may be reasonable under many conditions, several recent studies ha... View more
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