An EMT–Driven Alternative Splicing Program Occurs in Human Breast Cancer and Modulates Cellular Phenotype

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M. Shapiro, Irina; W. Cheng, Albert; C. Flytzanis, Nicholas; Balsamo, Michele; Condeelis, John S.; H. Oktay, Maja; B. Burge, Christopher; B. Gertler, Frank;
  • Publisher: Figshare
  • Related identifiers: doi: 10.1371/journal.pgen.1002218
  • Subject: Molecular Biology | phenotype | modulates | Genetics | cellular | cancer | splicing | occurs
    mesheuropmc: embryonic structures

<div><p>Epithelial-mesenchymal transition (EMT), a mechanism important for embryonic development, plays a critical role during malignant transformation. While much is known about transcriptional regulation of EMT, alternative splicing of several genes has also been corr... View more
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