The Caenorhabditis elegans Mucin-Like Protein OSM-8 Negatively Regulates Osmosensitive Physiology Via the Transmembrane Protein PTR-23

Collection UNKNOWN
Rohlfing, Anne-Katrin; Miteva, Yana; Moronetti, Lorenza; He, Liping; Lamitina, Todd;
(2011)
  • Publisher: Figshare
  • Related identifiers: doi: 10.1371/journal.pgen.1001267
  • Subject: Molecular Biology | role | animal cell osmoregulation | constitutive osmosensitive gene expression | Osm -8 phenotypes | stress resistance | Genetics | Evolutionary Biology | constitutive glycerol accumulation | Biophysics | Immunology | Transmembrane Protein PTR -23 | Caenorhabditis elegans mucin-like gene osm -8 | Developmental Biology | Physiology | novel transmembrane protein | Medicine | Caenorhabditis elegans Mucin-Like Protein OSM -8 Negatively Regulates Osmosensitive Physiology Via | mucin-plasma membrane interface | extracellular mucin-like protein | Cell Biology | hypertonic stress | Biochemistry | genome-wide RNAi osm -8 suppressor screen | osm -8 mutants exhibit resistance | osmoresponsive gene expression | Cancer | osm -8 mutants
    • FOR: 110309 Infectious Diseases | 69999 Biological Sciences not elsewhere classified | 60506 Virology
    mesheuropmc: fungi

<div><p>The molecular mechanisms of animal cell osmoregulation are poorly understood. Genetic studies of osmoregulation in yeast have identified mucin-like proteins as critical regulators of osmosensitive signaling and gene expression. Whether mucins play similar roles ... View more
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