Whole Genome Sequencing of Field Isolates Reveals a Common Duplication of the Duffy Binding Protein Gene in Malagasy Plasmodium vivax Strains

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Menard, Didier; R. Chan, Ernest; Benedet, Christophe; Ratsimbasoa, Arsène; Kim, Saorin; Chim, Pheaktra; Do, Catherine; Witkowski, Benoit; Durand, Remy; Thellier, Marc; Severini, Carlo; Legrand, Eric; Musset, Lise; Y. M. Nour, Bakri; Mercereau-Puijalon, Odile; Serre, David; A. Zimmerman, Peter;
  • Publisher: Figshare
  • Related identifiers: doi: 10.1371/journal.pntd.0002489
  • Subject: genome | malagasy | reveals | isolates | binding | strains | Biological Sciences | sequencing | duplication | duffy
    mesheuropmc: parasitic diseases

<div><p>Background</p><p><i>Plasmodium vivax</i> is the most prevalent human malaria parasite, causing serious public health problems in malaria-endemic countries. Until recently the Duffy-negative blood group phenotype was considered to confer resistance to vivax malar... View more
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