The Chromosomal Passenger Complex Activates Polo Kinase at Centromeres

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Carmena, Mar; Pinson, Xavier; Platani, Melpi; Salloum, Zeina; Xu, Zhenjie; Clark, Anthony; MacIsaac, Fiona; Ogawa, Hiromi; Eggert, Ulrike; Glover, David M.; Archambault, Vincent; Earnshaw, William C.;
  • Publisher: Figshare
  • Related identifiers: doi: 10.1371/journal.pbio.1001250
  • Subject: kinase | Cell Biology | Genetics | chromosomal | polo | Biochemistry | centromeres | activates
    mesheuropmc: biological phenomena, cell phenomena, and immunity | enzymes and coenzymes (carbohydrates)

<div><p>The coordinated activities at centromeres of two key cell cycle kinases, Polo and Aurora B, are critical for ensuring that the two sister kinetochores of each chromosome are attached to microtubules from opposite spindle poles prior to chromosome segregation at ... View more
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