Extensive Alternative Splicing of the Repressor Element Silencing Transcription Factor Linked to Cancer
Miller, Gregory M.
- Publisher: Figshare
Physics | Medicine | Biological Sciences | biochemistry | nucleic acids | rna | rna processing | computational biology | molecular genetics | gene regulation | biophysics | genetics | cancer genetics | epigenetics | gene splicing | molecular cell biology | gene expression | epidemiology | biomarker epidemiology | oncology | cancer risk factors | genetic causes of cancer | basic cancer research | splicing | repressor | transcription | linked
<div><p>The repressor element silencing transcription factor (REST) is a coordinate transcriptional and epigenetic regulator which functions as a tumor suppressor or an oncogene depending on cellular context, and a truncated splice variant REST4 has been linked to vario...