Assessment of Humoral Immune Responses to Blood-Stage Malaria Antigens following ChAd63-MVA Immunization, Controlled Human Malaria Infection and Natural Exposure

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Biswas, Sumi; Choudhary, Prateek; C. Elias, Sean; Miura, Kazutoyo; H. Milne, Kathryn; C. de Cassan, Simone; A. Collins, Katharine; D. Halstead, Fenella; M. Bliss, Carly; J. Ewer, Katie; H. Osier, Faith; H. Hodgson, Susanne; J. A. Duncan, Christopher; A. O’Hara, Geraldine; A. Long, Carole; V. S. Hill, Adrian; J. Draper, Simon;
  • Publisher: Figshare
  • Related identifiers: doi: 10.1371/journal.pone.0107903
  • Subject: AMA 1 antigens | Serum antibody responses | Biological Sciences | MSP 1 | CHMI | unimmunized control volunteers | Controlled Human Malaria Infection | malaria exposure | Humoral Immune Responses | mva | gia | antibody responses
    mesheuropmc: parasitic diseases

<div><p>The development of protective vaccines against many difficult infectious pathogens will necessitate the induction of effective antibody responses. Here we assess humoral immune responses against two antigens from the blood-stage merozoite of the <i>Plasmodium fa... View more
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