A Comprehensive Behavioral Test Battery to Assess Learning and Memory in 129S6/Tg2576 Mice

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Wolf, Andrea; Bauer, Björn; L. Abner, Erin; Ashkenazy-Frolinger, Tal; M. S. Hartz, Anika;
  • Publisher: Figshare
  • Related identifiers: doi: 10.1371/journal.pone.0147733
  • Subject: novel object recognition test | ad | arm water maze | Morris water maze | Comprehensive Behavioral Test Battery | rd 1 mutation | recessive rd 1 mutation | Tg 2576 mice | alternation task | Uncategorised | amyloid precursor protein | dementia mouse models | test battery
    mesheuropmc: mental disorders

<div><p>Transgenic Tg2576 mice overexpressing human amyloid precursor protein (hAPP) are a widely used Alzheimer’s disease (AD) mouse model to evaluate treatment effects on amyloid beta (Aβ) pathology and cognition. Tg2576 mice on a B6;SJL background strain carry a rece... View more
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