Integrating Macrophages into Organotypic Co-Cultures: A 3D In Vitro Model to Study Tumor-Associated Macrophages

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Linde, Nina; M. Gutschalk, Claudia; Hoffmann, Claudia; Yilmaz, Dilan; M. Mueller, Margareta;
  • Publisher: Figshare
  • Related identifiers: doi: 10.1371/journal.pone.0040058
  • Subject: Cell Biology | Immunology | Developmental Biology | Cancer | integrating | macrophages | organotypic | 3d | vitro | tumor-associated

<div><p>Tumor progression is controlled by signals from cellular and extra-cellular microenvironment including stromal cells and the extracellular matrix. Consequently, three-dimensional in vitro tumor models are essential to study the interaction of tumor cells with th... View more
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