Network Analyses Reveal Novel Aspects of ALS Pathogenesis

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Sanhueza, Mario; Chai, Andrea; Smith, Colin; A. McCray, Brett; Ian Simpson, T.; Taylor, J. Paul; Pennetta, Giuseppa;
  • Publisher: Figshare
  • Related identifiers: doi: 10.1371/journal.pgen.1005107
  • Subject: Uncategorised | ALS Pathogenesis Amyotrophic Lateral Sclerosis | network Analyses Reveal Novel Aspects | lipid droplet biogenesis | ALS pathogenesis | modifier | hVAPB function | drosophila | Motor neuron diseases

<div><p>Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by selective loss of motor neurons, muscle atrophy and paralysis. Mutations in the human VAMP-associated protein B (hVAPB) cause a heterogeneous group of motor neuron diseases... View more
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