Genetic and Physiological Activation of Osmosensitive Gene Expression Mimics Transcriptional Signatures of Pathogen Infection in C. elegans

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Rohlfing, Anne-Katrin; Miteva, Yana; Hannenhalli, Sridhar; Lamitina, Todd;
  • Publisher: Figshare
  • Related identifiers: doi: 10.1371/journal.pone.0009010
  • Subject: Genetics | Physiology | Immunology | physiological | activation | osmosensitive | mimics | transcriptional | signatures | pathogen

<div><p>The soil-dwelling nematode <em>C. elegans</em> is a powerful system for comparative molecular analyses of environmental stress response mechanisms. Infection of worms with bacterial and fungal pathogens causes the activation of well-characterized innate immune t... View more
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