Alpha 1 Antitrypsin Inhibits Dendritic Cell Activation and Attenuates Nephritis in a Mouse Model of Lupus
S. Elshikha, Ahmed
Mahdi, Mahmoud A.
- Publisher: Figshare
Molecular Biology | lupus-prone mouse model | over-reactive dendritic cells | bm-derived dc differentiation | tlr 9 agonist | Ecology | haat treatment | function | Immunology | tlr 4 agonist | type 1 diabetes | il | alpha 1 antitrypsin inhibits dendritic cell activation | Developmental Biology | mrl | tnf | sle | lps | serum autoantibody levels | Hematology | Cell Biology | arthritis mouse models | Biochemistry | Cancer | ifn-i | activation
mesheuropmc: skin and connective tissue diseases | immune system diseases
<div><p>Systemic lupus erythematosus (SLE) is an autoimmune disorder with a worldwide distribution and considerable mortality and morbidity. Although the pathogenesis of this disease remains elusive, over-reactive dendritic cells (DCs) play a critical role in the diseas...