Increased Cell Wall Teichoic Acid Production and D-alanylation Are Common Phenotypes among Daptomycin-Resistant Methicillin-Resistant Staphylococcus aureus (MRSA) Clinical Isolates

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Bertsche, Ute ; Yang, Soo-Jin ; Kuehner, Daniel ; Wanner, Stefanie ; N. Mishra, Nagendra ; Roth, Tobias ; Nega, Mulugeta ; Schneider, Alexander ; Mayer, Christoph ; Grau, Timo ; S. Bayer, Arnold ; Weidenmaier, Christopher (2013)
  • Publisher: Figshare
  • Related identifiers: doi: 10.1371/journal.pone.0067398
  • Subject: Biological Sciences | teichoic | d-alanylation | phenotypes | daptomycin-resistant | methicillin-resistant | isolates

<div><p>Multiple mechanisms have been correlated with daptomycin-resistance (<b>DAP-R</b>) in <i>Staphylococcus aureus</i>. However, one common phenotype observed in many DAP-R S<i>. Aureus</i> strains is a thickened cell wall (CW). The first evidence for an impact of C... View more
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