Mycobacterium tuberculosis nuoG Is a Virulence Gene That Inhibits Apoptosis of Infected Host Cells

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Velmurugan, Kamalakannan; Chen, Bing; L Miller, Jessica; Azogue, Sharon; Gurses, Serdar; Hsu, Tsungda; Glickman, Michael; R Jacobs Jr., William; A Porcelli, Steven; Briken, Volker;
(2007)
  • Publisher: Figshare
  • Related identifiers: doi: 10.1371/journal.ppat.0030110
  • Subject: Microbiology | Immunology | Cancer | tuberculosis | virulence | inhibits | apoptosis | infected | cells

<div><p>The survival and persistence of Mycobacterium tuberculosis depends on its capacity to manipulate multiple host defense pathways, including the ability to actively inhibit the death by apoptosis of infected host cells. The genetic basis for this anti-apoptotic ac... View more
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