Photoinduced Membrane Damage of E. coli and S. aureus by the Photosensitizer-Antimicrobial Peptide Conjugate Eosin-(KLAKLAK)2

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A. Johnson, Gregory; Ellis, E. Ann; Kim, Hansoo; Muthukrishnan, Nandhini; Snavely, Thomas; Pellois, Jean-Philippe;
(2014)
  • Publisher: Figshare
  • Related identifiers: doi: 10.1371/journal.pone.0091220
  • Subject: Medicine | Biological Sciences | Biochemistry | lipids | biotechnology | Bionanotechnology | microbiology | Bacterial pathogens | Escherichia coli | Gram positive | Gram negative | staphylococci | Microbial control | Microbial pathogens | Infectious diseases | Bacterial diseases | Staphylococcus aureus | photoinduced | membrane | photosensitizer-antimicrobial | peptide | conjugate

<div><p>Background/Objectives</p><p>Upon irradiation with visible light, the photosensitizer-peptide conjugate eosin-(KLAKLAK)<sub>2</sub> kills a broad spectrum of bacteria without damaging human cells. Eosin-(KLAKLAK)<sub>2</sub> therefore represents an interesting le... View more
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