The effect of montelukast in a model of gouty arthritis induced by sodium monourate crystals

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Ponce, Loida; Arjona, Marjorie; Blanco, Gustavo; Alvarez, Stuart; Arcila, Eduardo; Ortega, Arnaldo; Nuñez, Dubelis; Verzura, Julie; Tovar, Robert; Bethencourt, Sarah; Riera, Ricardo; Mora-Orta, Sioly; Corado, José;
  • Publisher: Universidad del Zulia
  • Subject: Acute gouty arthritis | air pouch | sodium monourate | montelukast | leukotrienes | Artritis gotosa aguda | bolsa de aire | monourato de sodio | Montelukast | leucotrienos

Non-steroidal anti-inflammatory drugs (NSAIDS) are the first line of therapy in acute gouty arthritis. NSAIDs inhibit the cyclooxygenase pathway, but not the lipooxygenase activity and can have many adverse effects and thus have a limited effect on the control of inflam... View more
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