research product . 2016

Pengaruh Pemberian Ekstrak Bunga Pepaya Jantan (Carica papaya L) Terhadap Parameter Farmakokinetika Natrium Diklofenak Menggunakan Data Urin

Ningsih S, Fusfita Arika;
Open Access Indonesian
  • Published: 28 Oct 2016
  • Country: Indonesia
Abstract
Pharmacokinetic profile connected with the entry of active substances into the body. This research is aimed to finding the effect of the male papaya flower extracts affect on the pharmacokinetics profile of diclofenac sodium The research was conducted using 20 male rats weighing of 150-200 g, were divided into four groups, the first group given diclofenac sodium standard solution of 2.25 mg/kg bw of extract then performed on the male papaya flowers of each group consisted of 5 rats with a dose 20 mg/kg bw, 40 mg/kg bw, 80 mg/kg bw orally for 7 days. Next given diclofenac sodium solution after 4 hours of administration of the ethanol extract of papaya flower male...
Subjects
free text keywords: Diclofenac sodium, ethanolic extract of male flower of papaya plants, pharmacokinetic profile, urine
Related Organizations
26 references, page 1 of 2

2.3 Farmakokinetika .............................................................

2.3.1 Absorpsi .................................................................

2.3.2 Distribusi ...............................................................

2.3.3 Metabolisme ..........................................................

2.3.4 Ekskresi .................................................................

2.4 Parameter Farmakokinetika Ekskresi Urin Kumulatif

3.1 Alat dan bahan

3.1.1 Alat-alat

3.1.2 Bahan-bahan

3.2 Penyiapan sampel

3.3 Pengambilan sampel

3.4 Identifikasi sampel

3.5 Pengolahan sampel

3.6 Pemeriksaan karakterisasi simplisia

3.6.1 Pemeriksaan makroskopik

26 references, page 1 of 2
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