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Non-cell autonomous choroid plexus-derived sAPPα regulates adult hippocampus proliferation and plasticity
[SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology
[SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology
- Inserm France
- Immunology, inflammation, infectiology and microbiology France
- Biology of Infection France
- Molecular and structural basis of life sciences France
- Department of Virology France
Baruch K, Deczkowska A, David E, Castellano JM, Miller O, Kertser A, Berkutzki T, Barnett-Itzhaki Z, Bezalel D, Wyss-Coray T, Amit I, Schwartz M (2014) Aginginduced type I interferon response at the choroid plexus negatively affects brain function. Science 346:89-93. doi: 10.1126/science.1252945 Bjornsson CS, Apostolopoulou M, Tian Y, Temple S (2015) It takes a village: constructing the neurogenic niche. Dev Cell 32:435-446. doi: 10.1016/j.devcel.2015.01.010 Caillé I, Allinquant B, Dupont E, Bouillot C, Langer A, Müller U, Prochiantz A (2004) Soluble form of amyloid precursor protein regulates proliferation of progenitors in the adult subventricular zone. Development 131:2173-2181. doi: 10.1242/dev.01103 Choi SH, Bylykbashi E, Chatila ZK, Lee SW, Pulli B, Clemenson GD, Kim E, Rompala A, Oram MK, Asselin C, Aronson J, Zhang C, Miller SJ, Lesinski A, Chen JW, Kim DY, van Praag H, Spiegelman BM, Gage FH, Tanzi RE (2018) Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer's mouse model. Science. doi: 10.1126/science.aan8821 D'Hooge R, De Deyn PP (2001) Applications of the Morris water maze in the study of learning and memory. Brain Res Brain Res Rev 36:60-90.
Deane R, Sagare A, Hamm K, Parisi M, Lane S, Finn MB, Holtzman DM, Zlokovic BV (2008) apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain. J Clin Invest 118:4002-4013. doi: 10.1172/JCI36663 Ernst A, Alkass K, Bernard S, Salehpour M, Perl S, Tisdale J, Possnert G, Druid H, Frisén J (2014) Neurogenesis in the striatum of the adult human brain. Cell 156:1072- 1083. doi: 10.1016/j.cell.2014.01.044 Falcão AM, Marques F, Novais A, Sousa N, Palha JA, Sousa JC (2012) The path from the choroid plexus to the subventricular zone: go with the flow! Front Cell Neurosci 6:34. doi: 10.3389/fncel.2012.00034 Fol R, Braudeau J, Ludewig S, Abel T, Weyer SW, Roederer J-P, Brod F, Audrain M, Bemelmans A-P, Buchholz CJ, Korte M, Cartier N, Müller UC (2016) Viral gene transfer of APPsα rescues synaptic failure in an Alzheimer's disease mouse model.
Acta neuropathologica 131:247-266. doi: 10.1007/s00401-015-1498-9 Sousa JC, Cardoso I, Marques F, Saraiva MJ, Palha JA (2007) Transthyretin and Alzheimer's disease: where in the brain? Neurobiol Aging 28:713-718. doi: 10.1016/j.neurobiolaging.2006.03.015 Spatazza J, Lee HHC, Di Nardo AA, Tibaldi L, Joliot A, Hensch TK, Prochiantz A (2013) Choroid-plexus-derived Otx2 homeoprotein constrains adult cortical plasticity.
Cell Rep 3:1815-1823. doi: 10.1016/j.celrep.2013.05.014 Suberbielle E, Sanchez PE, Kravitz AV, Wang X, Ho K, Eilertson K, Devidze N, Kreitzer AC, Mucke L (2013) Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β. Nat Neurosci. doi: 10.1038/nn.3356 Tan VTY, Mockett BG, Ohline SM, Parfitt KD, Wicky HE, Peppercorn K, Schoderboeck L, Yahaya MFB, Tate WP, Hughes SM, Abraham WC (2018) Lentivirus-mediated expression of human secreted amyloid precursor protein-alpha prevents development of memory and plasticity deficits in a mouse model of Alzheimer's disease. Mol Brain 11:7. doi: 10.1186/s13041-018-0348-9 Toda T, Parylak SL, Linker SB, Gage FH (2019) The role of adult hippocampal neurogenesis in brain health and disease. Mol Psychiatry 24:67-87. doi: 10.1038/s41380-018-0036-2 van Praag H, Christie BR, Sejnowski TJ, Gage FH (1999) Running enhances neurogenesis, learning, and long-term potentiation in mice. Proc Natl Acad Sci USA 96:13427-13431.
Wang B, Wang Z, Sun L, Yang L, Li H, Cole AL, Rodriguez-Rivera J, Lu H-C, Zheng H (2014) The amyloid precursor protein controls adult hippocampal neurogenesis 22 21 /)s 20 m (cd 19 e pe 18 S17 16 100 80 ()s 60 ieTm 40 20 0 20 ) 18 21 ) 20 s /cm 19 ( eed 18 p S 17 16 20 ) 18 s /cm16 ( eed 14 p S12 10
- Funder: European Commission (EC)
- Project Code: 339379
- Funding stream: FP7 | SP2 | ERC
- Inserm France
- Immunology, inflammation, infectiology and microbiology France
- Biology of Infection France
- Molecular and structural basis of life sciences France
- Department of Virology France
- Physiopathology, metabolism and nutrition France
- Health technologies France
- Biologie Structurale des Processus Cellulaires et des Agents Infectieux France
- Laboratoire d'Informatique Gaspard-Monge France
- Cancer France
- Public Health France
- Dynamic Neuronal Imaging France
- Laboratoire Modélisation et Simulation Multi-Echelle France
- University of Marne la Vallée France
- Cell Biology, Development and Evolution France
- Université Paris Diderot France
- Institut Pasteur France
- Neurosciences, cognitive sciences, neurology and psychiatry France
- Laboratoire d’Analyse et de Mathématiques Appliquées France
- Genetics, Genomics and Bioinformatics France
- Department of Genomes & Genetics France