research product . Collection . 2019

Pathobiology and innate immune responses of gallinaceous poultry to clade 2.3.4.4A H5Nx highly pathogenic avian influenza virus infection

Kateri Bertran; Pantin-Jackwood, Mary; Criado, Miria; Lee, Dong-Hun; Balzli, Charles; Spackman, Erica; Suarez, David; Swayne, David;
  • Published: 01 Jan 2019
  • Publisher: figshare
Abstract
Abstract In the 2014â 2015 Eurasian lineage clade 2.3.4.4A H5 highly pathogenic avian influenza (HPAI) outbreak in the U.S., backyard flocks with minor gallinaceous poultry and large commercial poultry (chickens and turkeys) operations were affected. The pathogenesis of the first H5N8 and reassortant H5N2 clade 2.3.4.4A HPAI U.S. isolates was investigated in six gallinaceous species: chickens, Japanese quail, Bobwhite quail, Pearl guinea fowl, Chukar partridges, and Ring-necked pheasants. Both viruses caused 80â 100% mortality in all species, except for H5N2 virus that caused 60% mortality in chickens. The surviving challenged birds remained uninfected based on ...
Subjects
Medical Subject Headings: animal structures
free text keywords: Medicine, Evolutionary Biology, Ecology, Immunology, Cancer, 110309 Infectious Diseases, 60506 Virology
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figshare
Collection . 2019
Provider: Datacite
figshare
Collection . 2019
Provider: Datacite
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