Oxacillin sensitization of methicillin-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus pseudintermedius by antisense peptide nucleic acids in vitro

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Shan Goh ; Anette Loeffler ; David Lloyd ; Sean Nair ; Liam Good (2015)
  • Publisher: Figshare
  • Related identifiers: doi: 10.6084/m9.figshare.c.3619610.v1
  • Subject: Molecular Biology | Biotechnology | Hematology | Cell Biology | Genetics | Biochemistry | Pharmacology | Microbiology | Cancer
    • FOR: 110309 Infectious Diseases | 60506 Virology
    mesheuropmc: biochemical phenomena, metabolism, and nutrition

Abstract Background Antibiotic resistance genes can be targeted by antisense agents, which can reduce their expression and thus restore cellular susceptibility to existing antibiotics. Antisense inhibitors can be gene and pathogen specific, or designed to inhibit a grou... View more
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